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stream; alteration of the distribution of blood in the body, namely from the abdominal viscera to viagra for men in hyderabad the heart, lungs, central viagra for men in hyderabad nervous system and limbs; the shortening of the coagulation viagra for men in hyderabad time of the blood. Regarding the increase of sugar in the viagra for men in hyderabad blood, due to emotion or excitement, the relation between "flight instinct" and "fear emotion" viagra for men in hyderabad and "pugnacity in- stinct" has been suggested. Since in wild life, fear and anger are likely to be followed by activities involving severe muscular exertion, probably the pouring out of sugar into viagra dosierung the blood is Nature's way of coming to the aid of the laboring muscles. Darwin has drawn our attention to the fact that a "man or animal driven through terror to despera- tion, is endowed with wonderful strength, and is notoriously dangerous in the highest degree." . . . "In the agony of pain," he says further, "almost every muscle of the body is brought into strong action." Crile has explained that with every injurj^ there is a discharge of nervous energy. According to his kinetic theory of shock, viagra for men in hyderabad the essential lesions of shock are in the brain cells. It is difficult to imagine the surgical shock of preanesthetic days. Inhalation anesthesia goes a long way toward miti- gating viagra for men in hyderabad the effect of surgical trauma upon the nervous system, by abolishing pain, which can be of no possible advantage to either patient or phy- sician. Pain of viagra for men in hyderabad surgical operation decreases the patient's resistance, exhausts his nervous energy, and delays convalescence. Crile has found experi- mentally that trauma, fear, and fatigue have simi- lar effects on the brain cells. It is his belief that inhalation anesthesia does not go far enough; he speaks of it as only a "veneer." He reduces surgi- cal shock to the minimum by eliminating fear and by the viagra dosierung employment of local anesthesia to block the nerve trunks. Crile's work is a distinct contribu- tion to viagra for men in hyderabad medicine in its efforts to overcome the effect of pain and surgical shock. Once pain has served its purpose as a diagnostic aid, it should be abolished for reasons which are self evident. REFERENCES. 1. The Birth and Death of Pain," a viagra dosierung poem read Octo- ber 16, 1896, at the coniniemoration of the fiftieth anni- versary of the first demonstration of surgical anes- thesia, in the Massachusetts General Hospital, by S. Weir Mitchell. 2. Loeb: Physiology of the Brain, page 213, et seq. 3. Cannon: Bodily Changes in Pain, Hunger, Fear, and Rage, 1915. September 4, 1915] MEDICAL RECORD. 403 viagra for men in hyderabad In addition to the authorities credited in this paper, the writer's grateful acknowledgements are accorded the excellent work of Behan, on Pain, which volume con- tains also an exhaustive biblography. 142 Missouri Avenue, COMPLEMENT FIXATION IN CHICKEN SAR- COMA.* By CHARLES H. BAILEY, M.D.. NEW YORK. The discovery by Rous of a tumor in fowls viagra for men in hyderabad which can be propagated by a filtrate made from crushed cells or by the powder of dried cells, showed that in these animals, at least, there exists a viagra for men in hyderabad new growth of a type entirely different from any as yet de- scribed, since no other tumors in animals, so far as is known, can be propagated by the means just men- tioned. The natural assumption would be that this tumor is produced by a virus which is filterable, since it has viagra for men in hyderabad been impossible, either by culture, by examining the fluid by ultramicroscopic methods, viagra for men in hyderabad or by the study of stained sections, to demonstrate any parasite. On the theory that if the growth were of parasitic origin the blood of the animal would contain a com- plement-fixing substance, the following viagra for men in hyderabad experiments were carried viagra dosierung out in the laboratory of the Crocker Special Research Fund at the suggestion of Dr. F. C. Wood. Sarcoma No. 1, which was kindly sup- plied by Dr. Rous, was viagra for men in hyderabad employed in these experi- ments. Fixation tests were done on the sei-a of six Plymouth Rock and two white Leghorn hens, all of which had large tumors, the tests being controlled in each instance by sera from normal hens of the same species. The antigens used were made by ex- tracting finely ground tumor tissue with (1) dis- tilled water; (2) normal salt solution; (3) 95 per cent, alcohol, and (4) absolute alcohol. In some cases the tests were carried out with an antigen made of tumor tissue obtained from the hen which furnished the blood ; in others they were performed with an antigen made from the tumors of the other hens. The general technique was the standard method now employed in carrying out the Wasser- mann reaction. In none of these e.xperiments was a positive complement-fixation test obtained. As a further control, blood from two pigeons which had been injected subcutaneously several times with the Rous chicken sarcoma, without takes, and from one normal pigeon, was inactivated by heating for twenty minutes at 55┬░ C. Each of these three sera was then tested and viagra for men in hyderabad found to be neither