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injection of neosalvarsan is dangerous, although a review of the literature leads to that opinion. The neosalvarsan has always been well diluted with spinal fluid before the injection and this may ob- viate some of its irrigating effect. It was possible to get the spinal fluid Wasser- mann negative in three cases. The amount of fluid used in these reactions was sri lanka viagra 1 c.c. Whether the Wassermann will remain negative it is not possible to state. The cell count was variable and although lower in all cases after treatment, this is not con- sidered a criterion of improvement. The three cases which became Wassermann negative were cases of primary optic atrophy, tabes, and tabo- paresis respectively. The case of optic atrophy be- came Wassermann negative after six intraspinal injections, three of undiluted salvarsanized serum heated at 56° and three of neosalvarsan direct (dosage six mg.). The oculist who examined this patient (Dr. Charles Lukens) states that his vision is improved by actual measurement, although the patient himself does not notice a great change for the better. The case of tabes showed after treat- ment a decrease in his ataxia, disappearance of pains, a general improvement in his well-being enabling him to go back to work. The third Was- sermann negative case (tabo-paresis) has shown a remarkable change in his mental state after seven intraspinal injections. The writer is convinced that these patients have been improved and feels that the method should be continued until its status sri lanka viagra is definitely determined. The relief of pain in patients getting but one or two injections has been noteworthy. This has hap- pened from the direct injection of neosalvarsan as well as from salvarsanized serum. This shows that the result js not nessarily due to the preliminary intravenous injection of salvarsan, as has been claimed. It is not possible to exclude a psycholog- ical effect in judging relief from such a symptom as pain. Patients who were getting morphine, however, did not require it any more and it seems that the relief of pain can be ascribed fairly to the intraspinal injection. It is the impression of the writer that much of the unfavorable opinion from this method of treatment has been based on cases treated insuflSciently. It is to be regretted that such persistency in treatment is necessary, and this fact may militate against sri lanka viagra its continued use. The writer believes that good results judged by the biological tests need not be anticipated unless five or six or more injections have been given. This number may be increased if necessary to twelve or fifteen before it is discarded as worthless in a given case. The following case reports give the spinal fluid before and after treatment: Case I. — Male, age 40. Tinsmith. Had primary in- fection at 21. Has ataxia, positive Remberg's sign, in- tense girdle and leg pains, numbness in extremities, 562 MIDICM. RECORD. [Oct. 2, 1915 negative Babinski, absent patellar reflex, and fixed pupils. Date Treatment Cell Count Xonne Spinal Wa. R. venta on line la viagra mas barata Feb. 6, 1914 April 9, 1914 Mav 9, 1914 Mav 23, 1914 Feb. 5. 1915 20 c.c. undiluted salvarsanized serum Ditto Ditto Ditto Ditto r.6 52 41 35 28 + + +